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Research

Apr 17, 2008

Raman lines up for in vivo imaging

Molecular imaging of living subjects is a hot topic, with fluorescence techniques in particular being developed for in vivo small-animal studies. But there's another option on the horizon: Raman spectroscopy. Raman offers some big advantages over fluorescence for biomedical applications - including high multiplexing capability and lack of background autofluorescence signal. Now, researchers at Stanford University School of Medicine (Stanford, CA) have used Raman spectroscopy to visualize nanoparticles deep within living animals (PNAS doi: 10.1073/pnas.0710575105).

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