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Protons plus photons: the optimal combination

With proton treatment slots a limited resource, could combined proton-photon therapy provide a suitable alternative?

Nanoparticles enable deep-brain manipulation

Flash physics: nanoparticles that convert NIR to blue-green light enable non-invasive modulation of neural activity deep inside the brain.

Cherenkov photo-activation enhances radiotherapy

Cherenkov light generated by clinical photon beams can activate light-sensitive drugs and enhance the efficacy of radiation treatments.

Treating Alzheimer's as a metabolic disease

Boosting mitochondrial defense reduces the formation of amyloid plaques in animal models of Alzheimer's disease.

Decellularized and recellularized grafts repair injured cartilage

Implanting decellularized cartilage loaded with stem cells improved the regeneration of injured cartilage in pigs.

A better way to test drinking water safety?

A fluorescence-based test of drinking water quality can detect bacterial contamination in just eight minutes.

Neural networks improve PET time-of-flight estimates

Convolutional neural networks improve the precision of time-of-flight estimates by up to 23% compared with conventional PET signal processing.

Cancer 'vaccine' eliminates tumours in mice

Flash physics: injecting immune-stimulating agents directly into a mouse tumour eliminated all cancer in the animal, including untreated metastases.

FDG-PET predicts outcomes in paediatric osteosarcoma

FDG-PET/CT scans predict chemotherapy outcomes in paediatric patients with osteosarcoma.

Could bee glue reduce infections on replacement joints?

Propolis, a bee product, harbours antibacterial compounds that can be transferred onto hydroxyapatite, a mineral used to replace lost bone.

Photon MLC collimates electron beams

Electron collimation using a photon MLC could improve clinical workflow and enable advanced delivery techniques.

Microbubbles increase tumour radiosensitivity

Flash physics: bursting oxygen-filled microbubbles within breast tumours increases oxygenation and almost triples radiosensitivity in animal models.

Tactile maps revealed following observed touch

Precise tactile activity maps are created in the somatosensory cortex when viewing someone else's fingers being touched.

Multisource CBCT enhances extremity imaging

A three-source cone-beam CT scanner improves the quality of extremity imaging.

Liver cancer organoids could enhance drug development

"Tumouroid" platforms advance liver cancer research and treatment.

Photonic technique eases cancer staging

Quantifying structural changes in nuclear DNA could simplify detection of cancerous cells and identify different stages of malignancy.

Molecular force microscopy: a new tool for measuring cellular forces

Researchers have developed a novel imaging technique that can map the magnitude and direction of cellular forces with piconewton resolution.

AAPM publishes guidelines for reporting Monte Carlo studies

Flash physics: AAPM Task Group develops guidelines to improve reporting of Monte Carlo simulations in medical physics research.

Adaptive system enhances robotic limb control

An adaptive control system for a robotic lower limb prosthesis adapts to the user's neural information while they walk.

3D printed scaffold replicates metastasis

A 3D printed model moves a step closer to the accurate reproduction of peritoneal metastasis.